Untangling the link between depression and gut disease

Oct. 22, 2026

Anteater Time Machine: Students compare notes, circa 1974.

Anteater Time Machine: Students compare notes, circa 1974. (Photo courtesy of UC Irvine Libraries Archives)

UC IRVINE NEWS

Curated with care

Clifford Danza, a first-year emergency medicine resident at Mass General Brigham and 2026 graduate of the UC Irvine School of Medicine, donated his digital artwork, “Mirror,” to the Crescent Clinic collection.

Warm earth tones and a nurturing touch. Billowing clouds reflected in a serene body of water. The grasp of a newborn baby’s tiny fingers. These are just a few of the thought-provoking scenes now shared throughout Crescent Clinic, a free healthcare clinic in Fullerton for underserved individuals. It now also provides a collection of original art and photography – a welcome distraction from the building’s otherwise barren white walls. This visual offering is the result of a project spearheaded by UC Irvine medical students Tatum Ego, co-chair of Crescent Clinic, and Zoe Adams, co-president and founder of UC Irvine’s Humanities Interest Group, along with the nonprofit Art for the Isolated, to create a more welcoming space.

Untangling the link between depression and gut disease

the study’s corresponding author, Gha-Hyun Jeffrey Kim (right), Pharm.D., Ph.D., UC Irvine assistant professor of clinical pharmacy practice.

Depression and gastrointestinal disorders frequently occur together. UC Irvine researchers wondered if knowing which tends to be diagnosed first could shed more light on the well-established but not yet fully understood gut-brain connection. Among patients with both diagnoses, depression was more often recorded before irritable bowel syndrome, while Crohn’s disease was more often recorded before depression. Ulcerative colitis showed a more mixed pattern. “These patterns can help inform what clinicians watch for – from persistent gut symptoms in patients with depression to changes in mood in patients with Crohn’s disease,” said Gha-Hyun Jeffrey Kim (above right), assistant professor of clinical pharmacy practice. The findings could help inform more tailored mental health and gastrointestinal screening rather than treating the gut-brain connection as a single, uniform relationship.

Hidden crisis of labor trafficking

a group of laborers working in a field

Angela Robinson, assistant researcher with UC Irvine’s Frontline Research to End Exploitation Institute, and Iza Camarillo, research director for the university’s Labor Center, have been awarded a $20,000 grant by the Collaborative to End Human Trafficking – a philanthropic organization co-founded by Susan Samueli and Carey Clawson – to address a persistent blind spot in the fight against human trafficking: the chronic undercounting of labor trafficking victims in Orange County. “Labor trafficking is fundamentally a workers’ rights issue, yet it often goes unrecognized within the very systems designed to protect workers,” said Camarillo. “By bringing a labor perspective to this research, we hope to better understand where those systems fall short and identify opportunities to strengthen protections for vulnerable workers.”

UC NEWS

SpeechMatters Podcast: Beyond the politics of viewpoint diversity

speech matters podcast graphic

In this episode of the SpeechMatters podcast, Milad Mohebali, assistant professor of educational administration at the University of Nebraska-Lincoln, and John Tomasi, Heterodox Academy president, discuss how the term viewpoint diversity has become polarizing and whether we can find common ground on the value of engaging with differing perspectives to foster student learning and the collective pursuit of truth.

UC leads the world in Nobel Prizes

Illustration of overlapping Nobel Prize medals featuring Alfred Nobel’s profile, in orange, blue and green against a yellow background.

UC's Nobel Prize winners have revealed the shape of DNA, how plants transform sunlight and air into new growth, how and why our bodies age, and the black hole that lurks at the center of our galaxy. These discoveries, many of which originated in federal funding, continue to shape daily life in surprising and amazing ways. Learn more about the innovations from UC’s world-leading Nobel legacy.

SAVE THE DATE

Image courtesy of Esther Gámez Rubio

Cauces Sónicos (Sonic Channels) is a two-year project exploring nodes of cross-border interaction among artistic communities, musical migration, intergenerational creativity and horizontal processes of teaching and learning.

Cauces Sónicos

Oct. 24, 8 p.m. (sponsored by Claire Trevor School of the Arts)


What will your story be?

Oct. 23, 10:30 a.m. (sponsored by School of Social Sciences)


Melodies of the Morning Calm

Oct. 25, 8 p.m. (sponsored by Claire Trevor School of the Arts)


Fourth Annual Paolo Sassone-Corsi Lectureship

Oct. 26, 5:30 p.m. (sponsored by Center for Epigenetics & Metabolism)


NSF BRIDGE Conference on Cyberinfrastructure for Collaborative Data Science and AI

Oct. 27, 1 p.m. (sponsored by Office of Research)


Winning hearts and minds: Lesions from Medical Education on Navigating misinformation, emotion and identity

Oct. 28, 11 a.m. (sponsored by UC National Center for Free Speech and Civic Engagement)


What Matters to Me and Why

Oct. 28, 6 p.m. (sponsored by UC Irvine Alumni)


HARMONICS 2026

Oct. 28-29, 8:30 a.m. (sponsored by School of Medicine)


For more events, visit UC Irvine Today.

#IamUCI

Knight of the Order of Academic Palms

Maryse Mijalski (above right), senior lecturer and French language program director, has been awarded the prestigious title of Knight of the Order of Academic Palms, one of France's oldest civilian honors

Maryse Mijalski (above right), senior lecturer and French language program director, has been awarded the prestigious title of Knight of the Order of Academic Palms, one of France's oldest civilian honors (it was established in 1808 by Emperor Napoleon!). Mijalski is being honored for her distinguished career and longstanding, exceptional contributions to education, as well as her commitment to promoting the French language, culture and academic excellence.

#UCIconnected spotlights interesting updates from the UC Irvine community. #IamUCI spotlights profiles of students, faculty, staff and alumni. Send submissions via email or post on social media with the #UCIconnected or #IamUCI hashtags.

UC IRVINE NEWSMAKERS

The New York Times logo

Alzheimer’s Researchers Look at an Unusual Data Point: Head Shape


The New York Times, Oct. 22

Cited: Michael Yassa, professor of neurobiology and behavior

Los Angeles Times logo

As companies leave California, is the state’s $4.25 trillion economy really in trouble?


Los Angeles Times, Oct. 22

Cited: David Neumark, Distinguished Professor of Economics

parade logo

Neurologists Say Normal Age-Related Forgetfulness Looks Different From the Memory Changes They Worry About


Parade, Oct. 21

Cited: Dr. Brian Hitt, UCI Health behavioral neurologist

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